Aims & Learning Objectives: Aims: To provide an overview of prokaryotic and eukaryotic genetic systems, to relate the genetics of microorganisms to their wider biological role, and give an indication of the diversity of genetic systems.
After taking this course the student should be able to:
*compare critically methods of mapping genes in both prokaryotes and eukaryotes
*understand the unity and diversity amongst bacterial plasmids
*explain the mechanism and implications of transposition
*provide a critical understanding of the molecular basis and types of recombination
*provide an account of the development of bacteriophage lambda with an understanding of the regulation of promoters and the nature of a genetic switch
*relate the possible evolutionary relationships between different replicating genetic elements.
Content: Topics: Advanced Mendelian genetics; recombination and repair; functional genomic analysis; extranuclear genetics of yeasts; genetics of bacterial plasmids; genetics and development of bacteriophage lambda; genetics of Archae.
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