Aims & Learning Objectives: This unit will familiarise the student with aspects of molecular signalling and current areas of research which are of particular interest and importance. Knowledge gained from previous units in cell biology, and in particular molecular pharmacology, will be built on with more advanced and specialised treatment of specific topics encompassing cellular signalling events in different model systems. After taking this unit the student should demonstrate an understanding of different cellular signalling mechanisms.
Content: Selected topics covering recent advances in molecular signalling. The areas to be covered include signalling events occuring in immune cells in response to cytokines and other mediators; protein interaction modules; kinase cascades; tyrosine kinases; tyrosine phosphatases; lipid signalling; regulation of transcription.
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