Department of Chemistry, Unit Catalogue 2010/11 |
CH20161: Drug properties 2 |
 Credits:
| 6 |
| Level:
| Intermediate |
| Period: | This unit is available in... |
| Semester 2 |
| Assessment:
| EX 100% |
| Supplementary Assessment: | Like-for-like reassessment (where allowed by programme regulations) |
| Requisites:
| Before taking this unit you must take CH10135 and take CH20160 and while taking this unit you must take CH20149 |
| Description:
| Aims: The unit will build on CH20160 to provide further teaching on the properties of drugs and some of the key aspects of medicinal chemistry which need to be considered by chemists involved in synthesising new drug molecules. Learning Outcomes: After studying the unit, students should be able to: * Provide examples of how anti-cancer drugs exert their effects in vivo; * Determine kinetic parameters for enzyme-catalysed reactions; * Recognise the importance of process chemistry and green chemistry to the drug discovery process. Skills: Numeracy (F, A). Problem solving (T, F, A). Scientific writing (F, A). Independent working (F). Group working (F). Content: Cell biology of cancer. The cell cycle. Common classes of anti-cancer drugs and their modes of action. Enzyme kinetics (Michaelis-Menten). Positive and negative co operativity. Process chemistry. Scale-up safety issues. Formulation. 12 Principles of green chemistry. Case studies. |