Department of Chemistry, Unit Catalogue 2010/11 |
CH30185: Drug properties for natural scientists |
 Credits:
| 6 |
| Level:
| Honours |
| Period: | This unit is available in... |
| Semester 1 |
| Assessment:
| CW20EX80 |
| Supplementary Assessment: | Supplementary assessment information not currently available (this will be added shortly) |
| Requisites:
| Before taking this unit you must take CH20150. This unit is only available to students on MSci programmes in Natural Sciences. |
| Description:
| Aims: The Unit will provide an introduction to the properties of drugs and some of the key aspects of medicinal chemistry which need to be considered by chemists involved in synthesising new drug molecules. Learning Outcomes: After studying the Unit, students should be able to: * identify common features of drug molecules * manipulate data to establish biokinetic parameters * illustrate the utility of 'log P' values and the importance of drug solubility * describe structure/activity relationships and understand how this aids the drug discovery process. Skills: Numeracy (F, A), Problem solving (T, F, A), Scientific writing (F, A), Independent working (F), Group working (F). Content: Properties of drugs described by the Lapinski rules. Introduction to biokinetics. Definition and use of log P and its relevance to bioavailability. Structure/activity relationships. Overview of successful drugs including antihistamines, antibacterial agents and agonists/antagonists of neurotransmitters. |