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CH30065: Biosynthesis & biotransformations

Follow this link for further information on academic years Academic Year: 2012/3
Follow this link for further information on owning departmentsOwning Department/School: Department of Chemistry
Follow this link for further information on credits Credits: 3
Follow this link for further information on unit levels Level: Honours (FHEQ level 6)
Follow this link for further information on period slots Period: Semester 2
Follow this link for further information on unit assessment Assessment: EX 100%
Follow this link for further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Follow this link for further information on unit rules Requisites: Before taking this unit you must take CH30128
Follow this link for further information on unit content Description: Aims:
To provide an introduction to advanced aspects of a topic of current interest in Organic Chemistry.

Learning Outcomes:
After studying this Unit, students should be able to:
* Provide examples of biosynthetic pathways.
* Describe how enzymes can be used to produce enantiomerically pure compounds.

Skills:
Problem solving (T, F, A). Scientific writing (F, A). Independent working (F). Group working (F).

Content:
Biotransformations. The use of enzymes in organic synthesis. Kinetic resolution with hydrolytic enzymes, and the preparation of enantiomerically enriched alcohols and acids. Enzymes in oxidation, reduction and C-C bond forming reactions. Biosynthetic pathways, including the biosynthesis of fatty acids and polyketides. Terpene biosynthesis, the shikimic acid pathway and the roles of pyridoxal phosphate in biosynthesis are also addressed.
Follow this link for further information on programme availabilityProgramme availability:

CH30065 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AFB07 : BSc (hons) Chemistry for Drug Discovery (Full-time) - Year 3
  • USCH-AKB08 : BSc (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB08 : BSc (hons) Chemistry for Drug Discovery with Study Year abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AFM05 : MChem (hons) Chemistry for Drug Discovery (Full-time) - Year 3

CH30065 is Optional on the following programmes:

Programmes in Natural Sciences
  • UXXX-AFB01 : BSc (hons) Natural Sciences (Full-time) - Year 3
  • UXXX-AKB02 : BSc (hons) Natural Sciences with Industrial Placement (Full-time with Thick Sandwich Placement) - Year 4
  • UXXX-AAB02 : BSc (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
  • UXXX-AFM01 : MSci (hons) Natural Sciences (Full-time) - Year 3
  • UXXX-AKM02 : MSci (hons) Natural Sciences with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • UXXX-AAM02 : MSci (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.