|
![]() | 2012/3 |
![]() | Department of Chemistry |
![]() | 3 |
![]() | Honours (FHEQ level 6) |
![]() |
Semester 2 |
![]() | EX 100% |
![]() | Like-for-like reassessment (where allowed by programme regulations) |
![]() | Before taking this unit you must take CH20149 or take CH20150 and in taking this unit you cannot take CH40068 |
![]() | Aims & Learning Objectives: To revise some basic concepts in physical organic chemistry and develop a number of ideas used to correlate reactivity and mechanism in a range of organic reactions. After studying the Unit, students should be able to: * Describe some experimental tools for investigating reaction mechanisms and the use of some theoretical models for their correlation and interpretation * Solve a range of problems involving numerical and mechanistic information Content: Energy changes in equilibria and reactivity. Transition states and saddle points. Activation parameters. Analysis of reaction coordinates. Principle of Least Nuclear Motion. Hammond Postulate. More O'Ferrall - Jencks diagrams. Rate - equilibrium correlations. Hammett equation as an example of a linear free-energy relationship. Signficance of s and r for reactivity and mechanism. Complex Hammett plots : change in mechanism vs. change in rate-determining step. Equilibrium and kinetic isotope effects. Primary and secondary effects and their significance. Heavy-atom effects. Solvent isotope effects. |
![]() |
CH30068 is Optional on the following programmes:Department of Chemistry
|