 Academic Year:
| 2012/3 |
| Owning Department/School:
| Department of Chemistry |
| Credits:
| 3 |
| Level:
| Honours (FHEQ level 6) |
| Period: |
Semester 1
|
| Assessment:
| EX 100% |
| Supplementary Assessment: | Like-for-like reassessment (where allowed by programme regulations) |
| Requisites:
| Before taking this unit you must take CH20149 or take CH20150. In taking this unit you cannot take Stereoselective Organic Synthesis as a component of CH30061. |
| Description:
| Aims:
The aim of the unit is to give students a thorough grounding in the methods, strategies and reagents employed in modern stereoselective organic synthesis.
Learning Outcomes:
After studying this unit students should be able to:
* Analyse the stereochemical course of a variety of reactions
* Describe reagent systems to effect a wide range of simple transformation
* Describe fully the mechanism of these reactions
* Apply the information learnt to solve problems.
Skills:
Problem solving (T, F, A)
Scientific writing (F, A), Independent working (f)
Group working (F)
Content:
The unit begins with a section concerned with simple diastereoselection, focusing on the reactions of carbonyl and alkene systems. The concepts of allylic strain and directed reactions are introduced. The use of chiral auxiliaries to control the stereochemistry of organic reactions forms the second section. Particular systems studied include the use of SAMP and RAMP hydrazones and Evans� auxiliaries to control a range of chiral-enolate based bond constructions.
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Programme availability:
|
CH30128 is Compulsory on the following programmes:
Department of Chemistry
- USCH-AFB01 : BSc (hons) Chemistry (Full-time) - Year 3
- USCH-AFB07 : BSc (hons) Chemistry for Drug Discovery (Full-time) - Year 3
- USCH-AKB08 : BSc (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
- USCH-AAB08 : BSc (hons) Chemistry for Drug Discovery with Study Year abroad (Full-time with Study Year Abroad) - Year 4
- USCH-AFB09 : BSc (hons) Chemistry with Education (Full-time) - Year 3
- USCH-AKB02 : BSc (hons) Chemistry with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
- USCH-AAB02 : BSc (hons) Chemistry with Study Year abroad (Full-time with Study Year Abroad) - Year 4
- USCH-AFM02 : MChem (hons) Chemistry (Full-time) - Year 3
- USCH-AFM05 : MChem (hons) Chemistry for Drug Discovery (Full-time) - Year 3
CH30128 is Optional on the following programmes:
Department of Chemistry
- USCH-AFB03 : BSc (hons) Chemistry with Management (Full-time) - Year 3
- USCH-AKB04 : BSc (hons) Chemistry with Management with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
- USCH-AAB04 : BSc (hons) Chemistry with Management with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
- USCH-AFM07 : MSci (hons) Chemistry with Management (Full-time) - Year 3
- USCH-AKM07 : MSci (hons) Chemistry with Management with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
Programmes in Natural Sciences
- UXXX-AFB01 : BSc (hons) Natural Sciences (Full-time) - Year 3
- UXXX-AKB02 : BSc (hons) Natural Sciences with Industrial Placement (Full-time with Thick Sandwich Placement) - Year 4
- UXXX-AAB02 : BSc (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
- UXXX-AFM01 : MSci (hons) Natural Sciences (Full-time) - Year 3
- UXXX-AKM02 : MSci (hons) Natural Sciences with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
- UXXX-AAM02 : MSci (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
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