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CH30211: Chemistry beyond the molecule

Follow this link for further information on academic years Academic Year: 2013/4
Further information on owning departmentsOwning Department/School: Department of Chemistry
Further information on credits Credits: 3
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment: EX 100%
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this unit you must take CH20149 or take CH20150. This unit is not available to students on placement or study abroad programmes.
Further information on descriptions Description: Aims:
To teach aspects of supramolecular chemistry with an emphasis on (bio)chemical recognition and sensing.

Learning Outcomes:
After taking this course the student should be able to:
* Identify and discriminate the relevant supramolecular interactions based on the solvent system;
* Describe analytical techniques used to investigate supramolecular interactions;
* Understand the role of solvation in molecular recognition and chemical reactivity;
* Describe dynamic combinatorial chemistry;
* Explain the enthalpic and entropic contributions in molecular recognition;
* Identify and describe different types of sensors;
* Design basic on/off and off/on molecular sensors;
* Explain the difference between sensing and sequestering;
* Describe molecular carriers and cellular channels and their mode of action.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Numeracy & computation T/F/A, Problem solving T/F, Information handling & retrieval T/F/A, Working independently T/F, Career preparation T/F.

Content:
Supramolecular Chemistry: Concepts and definition; Classification of supramolecular interactions; Cooperativity, effective molarity and chelate effect; Highlights of supramolecular interactions in nature. Solvation and solvophobic effects. Characterisation of supramolecular systems. Supramolecular chemistry through design: Small molecule receptors; Small molecule guests for biological targets; Supramolecular polymers. Dynamic combinatorial chemistry: Types of reversible chemistry; Analytical methods. Solution Host-Guest Chemistry: Cation receptors; Anion receptors; Neutral molecule receptors; Ditopic receptors. Sensors. Natural and artificial channels.
Further information on programme availabilityProgramme availability:

CH30211 is Optional on the following programmes:

Department of Chemistry
  • USCH-AFB01 : BSc (hons) Chemistry (Full-time) - Year 3
  • USCH-AFB07 : BSc (hons) Chemistry for Drug Discovery (Full-time) - Year 3
  • USCH-AKB08 : BSc (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB08 : BSc (hons) Chemistry for Drug Discovery with Study Year abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AFB09 : BSc (hons) Chemistry with Education (Full-time) - Year 3
  • USCH-AKB02 : BSc (hons) Chemistry with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AFB03 : BSc (hons) Chemistry with Management (Full-time) - Year 3
  • USCH-AKB04 : BSc (hons) Chemistry with Management with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB04 : BSc (hons) Chemistry with Management with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AAB02 : BSc (hons) Chemistry with Study Year abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AFM02 : MChem (hons) Chemistry (Full-time) - Year 3
  • USCH-AFM05 : MChem (hons) Chemistry for Drug Discovery (Full-time) - Year 3
  • USCH-AFM07 : MSci (hons) Chemistry with Management (Full-time) - Year 3
  • USCH-AKM07 : MSci (hons) Chemistry with Management with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
Programmes in Natural Sciences
  • UXXX-AFB01 : BSc (hons) Natural Sciences (Full-time) - Year 3
  • UXXX-AKB02 : BSc (hons) Natural Sciences with Industrial Placement (Full-time with Thick Sandwich Placement) - Year 4
  • UXXX-AAB02 : BSc (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
  • UXXX-AFM01 : MSci (hons) Natural Sciences (Full-time) - Year 3
  • UXXX-AKM02 : MSci (hons) Natural Sciences with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • UXXX-AAM02 : MSci (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4

Notes:
* This unit catalogue is applicable for the 2013/4 academic year only. Students continuing their studies into 2014/15 and beyond should not assume that this unit will be available in future years in the format displayed here for 2013/14.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.