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PA20046: Ethics and experimental pharmacology

Follow this link for further information on academic years Academic Year: 2014/5
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 12
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment Summary: CW 60%, EX 40%
Further information on unit assessment Assessment Detail:
  • Coursework (CW 85% - Qualifying Mark: 40)
  • Practicals (PR 15% - Qualifying Mark: 40)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: After taking this unit you must take PA20047
Further information on descriptions Description: Aims:
To introduce the student to the practical techniques used to study the autonomic nervous system, neurotransmission in smooth muscles and the cardiovascular system. To introduce the student to the concepts of radiation and radioactivity. To introduce the student to statistical data analysis. To provide proper education and training to carry out procedures on animals for scientific purposes.

Learning Outcomes:
After taking this unit, the student will demonstrate an understanding of the methods available to study drug effects on these systems and ability to individually conduct experiment using the organ bath method. Student will also undertake Home Office (HO) Module certification allowing a HO personal licence to be obtained.

Skills:
Scientific and practical skills (T/F/A) Statistical analysis of experimental data (T/F/A) Radioactivity calculations (T/F/A) Study skills, handling information, working with others (T/F) Problem solving (T/F).

Content:
Investigation of the effect of parasympathetic neurotransmission, cholinergic receptors, ganglion blocking drugs and muscarinic receptor antagonists, sympathetic neurotransmission, adrenoceptors and ion channels inhibitors in autonomic nerves and smooth muscle. Investigation of inotropic and chronotropic effects of drugs on cardiac preparations. Investigation of principal mechanisms controlling blood vessel diameter. Perform basic statistical analysis of experimental data. Perform basic radioactivity calculations. The unit also contains accredited Home Office Module (1-4) training.
Further information on programme availabilityProgramme availability:

PA20046 is Compulsory on the following programmes:

Department of Pharmacy & Pharmacology
  • USPA-AFB02 : BSc(Hons) Pharmacology (Year 2)
  • USPA-AKB02 : BSc(Hons) Pharmacology with Year long work placement (Year 2)
  • USPA-AKM02 : MPharmacol(Hons) Pharmacology with Year long work placement (Year 2)

Notes:
* This unit catalogue is applicable for the 2014/15 academic year only. Students continuing their studies into 2015/16 and beyond should not assume that this unit will be available in future years in the format displayed here for 2014/15.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.