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 Academic Year: | 2016/7 |
| Owning Department/School: | Department of Biology & Biochemistry |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
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| Assessment Summary: | CW 20%, EX 80% |
| Assessment Detail: |
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| Supplementary Assessment: |
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| Requisites: | Before taking this module you must take BB10007 OR take BB10214 |
| Description:
| Aims: To introduce students to further concepts of genomics relevant to transcriptomics and proteomics. Learning Outcomes: After taking this course the student should be able to: * Explain how whole genome transcriptome information is generated and analysed * Explain the type of biological information that is contained in genome level gene expression profiles * Relate gene expression profiles to the basic mechanisms of regulating gene expression * Explain how gene expression profiling can be used to investigate some disease processes. Skills: Knowledge and understanding T/F/A, Intellectual skills F/A, Written communication T/F/A, Numeracy F/A, Data acquisition, handling, and analysis T/F/A, Information technology T/F, Working independently T/F Content: Genome wide assessment of gene expression; Comparison of transcriptome data to identify aberrant gene expression patterns of genes and/or pathways in disease states; Comparative genomics combined with transcriptomics to gain insights into the molecular basis of clinically-relevant traits; Proteomics, structural genomics, protein disorder; Gene co-expression and protein-protein networks as means to identify functional interactions among genes; Epigenetics and disease, imprinting and genome-wide assessments of epigenetic markers; Applications of genomics analyses and ethical considerations: Legal applications, pharmacogenomics (diagnostic tools and treatment development), GM crops, etc. |
| Programme availability: |
BB20220 is Optional on the following programmes:Department of Biology & Biochemistry
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Notes:
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