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 Academic Year: | 2016/7 |
| Owning Department/School: | Department of Biology & Biochemistry |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
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| Assessment Summary: | EX 80%, PR 20% |
| Assessment Detail: |
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| Supplementary Assessment: |
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| Requisites: | Before taking this module you must take BB10003 OR take BB10004 OR take BB10121 |
| Description:
| Aims: To provide basic understanding of the factors that cause a protein to fold and the properties of those folds. To explore current methods for determining protein structures, folds and assemblies. Learning Outcomes: After taking this course the student should be able to: * Describe qualitatively the interactions that determine the native conformation of a protein and its stability. * Describe the form, occurrence and function of protein folds * Describe the process and application of spectroscopic and diffraction techniques to the investigation of molecular structures and assemblies. * Compare the relative advantages and limitations of these techniques and the data they provide. * propose appropriate experiments for given structural questions. Skills: Learning and studying T/F/A, Written communication T/F/A, Numeracy & computation T/F/A, Laboratory skills T/F, Information technology T/F, Information handling & retrieval T/F/A, Working independently T/F, Group working T/F. Content: Principles of protein folding Protein folds Methods and application of X-ray crystallography to protein structure. Methods and application of NMR spectroscopy to protein structure. Application of structural data to medicine and drug discovery At the end of this unit, students should be in a position to read and analyse primary literature concerning protein structures. This unit will build on first year introductory material to protein structure and methods for studying properties of proteins. It will assume knowledge of levels of protein structure, amino acid names and chemistry and methods for expressing and purifying proteins. It is designed for students doing the core Biochemistry units, but other students wishing to choose it as an option may do so as long as they are aware that this knowledge is expected. |
| Programme availability: |
BB20020 is Compulsory on the following programmes:Department of Biology & Biochemistry
BB20020 is Optional on the following programmes:Department of Biology & Biochemistry
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Notes:
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