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 Academic Year: | 2016/7 |
| Owning Department/School: | Department of Biology & Biochemistry |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
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| Assessment Summary: | EX 100% |
| Assessment Detail: |
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| Supplementary Assessment: |
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| Requisites: | Before taking this module you must take BB10007 OR take BB10214 |
| Description:
| Aims: To introduce students to the concepts of genomics. Learning Outcomes: After taking this course the student should be able to: * Explain how genome sequences are generated, analysed and annotated * Describe the type of biological information that is contained within an annotated genome sequence * Describe the gross differences between features of genome sequences from different types of organisms * Explain how to effectively access publicly accessible genomic resources using web portals to obtain relevant genomic information. Skills: Knowledge and understanding T/F/A, Intellectual skills F/A, Written communication T/F/A, Numeracy F/A, Data acquisition, handling, and analysis T/F/A, Information technology T/F, Working independently T/F Content: Genome sequencing of bacteria and eukaryotes; Sequencing, genome assembly, and genome annotation; Sequence alignment; Comparative genomics in bacteria and eukaryotes and its applications; Uses of comparative genomics on gene and exon annotation, interpretation of variation in sequence rate of evolution (protein rates of evolution, dN/dS); Gene family evolution and gene turnover patterns; Whole genome sequence alignment and the identification of ultra-conserved regions, genomic rearrangements, horizontal gene transfer, and intra-species genomic variation; Analyses of human migration and genome-wide association studies; Non-human intra-species variation (parasites, pathogens, etc.); Forensic genomics, microsatellites, SNPs, and copy number variation; Metagenomics biodiversity and microbiomes; Biodiversity, effects of climate change and pollution on biodiversity, bioremediation, human microflora interactions, effects of lifestyle and diet on microflora. |
| Programme availability: |
BB20219 is Optional on the following programmes:Department of Biology & Biochemistry
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Notes:
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