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 Academic Year: | 2016/7 |
| Owning Department/School: | Department of Pharmacy & Pharmacology |
| Credits: | 9 [equivalent to 18 CATS credits] |
| Notional Study Hours: | 180 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
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| Assessment Summary: | ES20EX80 |
| Assessment Detail: |
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| Supplementary Assessment: |
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| Requisites: | |
| Description:
| Aims: To familiarise the students with the pathogenic mechanisms of infectious disease, the human host response to infection and the pharmacology of anti-infective agents; to describe the molecular and cellular mechanisms associated with acute and chronic inflammation, to illustrate the pathology of chronic inflammatory diseases and to introduce the pharmacology of anti-inflammatory and immunosuppressive drugs and biological agents; to illustrate clinical cases through problem-based learning. Learning Outcomes: After taking this unit, the student will be able to * Describe the innate, adaptive and inflammatory host defence mechanisms against infectious agents * List the key features required by micro-organisms to cause human disease * Explain the role of excessive stimulation of host defence mechanisms in themselves causing human disease; * Justify the use of pharmacology of agents targeted at the exogenous infection or endogenous host defence response, * Explain the uses and limitations of antibodies in the laboratory and in the diagnosis and treatment of disease * Apply their knowledge of host defence mechanisms to interpret clinical case studies. Skills: Scientific and practical skills (T/F/A) Study skills, handling information, working with others (T/F) Problem solving (T/F) Written skills (T/F/A). Content: * The innate and adaptive immune system - antibodies, T and B lymphocytes, antigen presenting cells and the MHC, effector functions, * Mechanisms by which micro-organisms cause infectious disease. * Pharmacology of anti-infective compounds. * Mechanisms of tolerance and autoimmunity, acute and chronic inflammation, * Pharmacology of anti-inflammatory and anti-rheumatic agents and potential novel therapeutic approaches. * Use of antibodies as laboratory, diagnostic and therapeutic agents. * Problem based learning applied to relevant clinical case studies. |
| Programme availability: |
PA20345 is Compulsory on the following programmes:Department of Pharmacy & Pharmacology
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