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Course & Unit Catalogues


MA50063: Mathematical biology 2

[Page last updated: 23 October 2023]

Academic Year: 2023/24
Owning Department/School: Department of Mathematical Sciences
Credits: 6 [equivalent to 12 CATS credits]
Notional Study Hours: 120
Level: Masters UG & PG (FHEQ level 7)
Period:
Semester 2
Assessment Summary: CW 25%, EX 75%
Assessment Detail:
  • Coursework (CW 25%)
  • Examination (EX 75%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites:
Learning Outcomes: At the end of this unit, students should be able to:
* Derive and interpret mathematical models of problems arising in biology using partial differential equations
* Analyse models written in terms of partial differential equations
* Give a qualitative and quantitative account of their solution, and
* Interpret the results in terms of the original biological problem
* Discuss the ideas presented in this unit orally to demonstrate in-depth understanding of the material.


Aims: To introduce students to applications of partial differential equations to model problems arising in biology. Both mathematical modelling and mathematical analysis will be covered, and at all times the interplay between the mathematics and the underlying biological concepts will be emphasised.

Skills: Mathematical modelling in biology T/F A
Problem solving T/F A
Written communication F A

Content: : Biological Motion
* Derivation of general conservation equation (macroscopic approach)
* Properties of a conservation equation
* Boundary conditions
* Derivation of the diffusion-advection equation (microscopic approach)
* Components of flux - diffusion, advection, chemotaxis
* Solution of the advection equation using method of characteristics
* Age structured problems
* Solutions of the diffusion equation using the fundamental solution
* Steady state distributions; transit times
Biological Invasions
* Wavefront and wavespeed calculations for exponentially growing populations
* Planar travelling waves; minimum wavespeed
Spatial Pattern Formation
* Critical domain size; scale and geometry effects
* Turing mechanisms
* Linear stability analysis; conditions for diffusion-driven instability; dispersion relation and Turing space.
Tumour Growth
* Formation of necrotic core
* Tumour size.

Course availability:

MA50063 is Optional on the following courses:

Department of Mathematical Sciences

Notes:

  • This unit catalogue is applicable for the 2023/24 academic year only. Students continuing their studies into 2024/25 and beyond should not assume that this unit will be available in future years in the format displayed here for 2023/24.
  • Courses and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
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