SL22015: Molecular biochemistry
[Page last updated: 03 June 2024]
| Academic Year: | 2024/25 |
| Owning Department/School: | Department of Life Sciences |
| Credits: | 10 [equivalent to 20 CATS credits] |
| Notional Study Hours: | 200 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
- Academic Year
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| Assessment Summary: | CWRI 20%, EXIC 20%, EXOB 60% |
| Assessment Detail: |
- MCQ (EXIC 20%)
- Report Individual (CWRI 20%)
- Open-book written examination (EXOB 60%)
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| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
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| Requisites: |
Before taking this module you must take SL12001 AND ( take CH12001 OR take CH12002 )
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| Learning Outcomes: |
By the end of this unit you will be able to:
- Outline key concepts and theories in physical biochemistry.
- Demonstrate your understanding of enzyme catalysis including classical and quantum mechanical phenomena.
- Explain the science underlying modern biochemical techniques and how they can be used to analyse proteins.
- Analyse, process and interpret numerical data from common and more advanced methodologies.
- Apply your knowledge and understanding of core concepts in molecular biochemistry to applied biochemistry advances.
- Explain emerging concepts in molecular biochemistry.
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| Synopsis: | Youwillbeintroduced tomore advanced molecular concepts in biochemistry. Core principles in physical, organic and inorganic chemistry will be applied to key examples, primarily from proteins, notably enzymes, also other key biomolecular systems.Youwill consider the application of these principles in the development and design of biocatalysts and medicines.Advanced experimental/computational approaches will illustrate molecular biochemistry as an applied discipline.
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| Content: | Biochemical techniques:
These will include single molecule spectroscopy, computational biochemistry and others
Applied advances could include biocatalysis, medicine design, new analytical techniques
Problem definition:
Enzyme kinetics,
Thermodynamics,
Protein chemistry,
Enzyme reaction mechanism,
Protein folding
Inorganic cofactors and catalytic strategies
Strategies for drug design
Experimental and computational techniques
Processing, manipulating and interpreting data
Applied examples and understanding the route to commercial application
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| Course availability: |
SL22015 is Compulsory on the following courses:
Department of Life Sciences
- USSL-AFB10 : BSc(Hons) Biochemistry (Year 2)
- USSL-AKB10 : BSc(Hons) Biochemistry with professional placement (Year 2)
- USSL-AFM10 : MBiochem(Hons) Biochemistry (Year 2)
- USSL-AKM10 : MBiochem(Hons) Biochemistry with professional placement (Year 2)
SL22015 is Optional on the following courses:
Department of Chemistry
- USSC-AFB10 : BSc(Hons) Natural Sciences (Biochemistry and Chemistry) (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biochemistry and Chemistry) with Study year abroad (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biochemistry and Chemistry) with professional placement (Year 2)
- USSC-AFB10 : BSc(Hons) Natural Sciences (Biochemistry and Pharmacology) (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biochemistry and Pharmacology) with Study year abroad (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biochemistry and Pharmacology) with professional placement (Year 2)
- USSC-AFM10 : MSci(Hons) Natural Sciences (Biochemistry and Chemistry) (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biochemistry and Chemistry) with professional placement (Year 2)
- USSC-AFM10 : MSci(Hons) Natural Sciences (Biochemistry and Pharmacology) (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biochemistry and Pharmacology) with Study year abroad (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biochemistry and Pharmacology) with professional placement (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 2)
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Notes: - This unit catalogue is applicable for the 2024/25 academic year only. Students continuing their studies into 2025/26 and beyond should not assume that this unit will be available in future years in the format displayed here for 2024/25.
- Courses and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
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