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SL52130: Organic, medicinal and pharmaceutical chemistry

[Page last updated: 15 August 2024]

Academic Year: 2024/25
Owning Department/School: Department of Life Sciences
Credits: 15 [equivalent to 30 CATS credits]
Notional Study Hours: 300
Level: Masters UG & PG (FHEQ level 7)
Period:
Semester 1
Assessment Summary: CWRI 40%, EXOB 60%
Assessment Detail:
  • Exam (EXOB 60%)
  • Coursework (CWRI 8%)
  • Coursework (CWRI 16%)
  • Coursework (CWRI 16%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: While taking this module you must take SL52128
Learning Outcomes: After studying this unit, students should be able to: Demonstrate knowledge of and competency in key laboratory skills Demonstrate skills in planning and executing practical problems in organic chemistry Work in a team allocating and correlating tasks and ensuring accurate collection of data Generate, analyse and interpret data collected Assemble and present the results of an investigation Demonstrate experimental skills required for the research project in semester 3 Describe a range of current spectroscopic techniques and understand experimental data derived from spectroscopic experiments; Compare techniques and bring together results from different experiments Solve problems using the methods introduced including the application of techniques to unseen situations, particularly organic molecules or medicinal relevance Illustrate how the structure and bonding of simple organic molecules explains their chemical behaviour Apply nomenclature, notation and diagrams to describe structures and reactions Explain the mechanisms and reagents required for key transformations


Synopsis: You will develop your core knowledge of organic, medicinal and pharmaceutical chemistry. You will develop the ability to apply this knowledge to carry out laboratory-based investigations.

Content: Structural and electronic properties. Stereochemistry and stereospecificity. Physical organic chemistry. Physicochemical properties of drug compounds Characteristic reactions of alkenes and haloalkanes, reactions of carbonyls, fundamental metal catalysed transformations. Spectroscopy principles and analysis of NMR, IR, Mass Spectrometry, X-ray, UV etc. Application of techniques to identify compounds, culminating in the identification of a variety of compounds using various forms of analytical data provided. The practical element of the course will build on the knowledge gained in classes and workshops of organic synthesis for drug targets and spectroscopic techniques. This will begin with pre-set experimental methods to develop laboratory skills in experimental set-up, purification and analysis. Finally, a problem will be set and appropriate experimental protocols will need to be researched and designed. After completion of the work, a variety of reporting formats will be used to emphasise scientific communication skills.

Course availability:

SL52130 is Optional on the following courses:

Department of Life Sciences

Notes:

  • This unit catalogue is applicable for the 2024/25 academic year only. Students continuing their studies into 2025/26 and beyond should not assume that this unit will be available in future years in the format displayed here for 2024/25.
  • Courses and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.